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Transcription Factor E3 (TFE3) (Middle Region) Peptid

TFE3 Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN5511608
  • Target Alle TFE3 Produkte
    TFE3 (Transcription Factor E3 (TFE3))
    Protein Region
    Middle Region
    Spezies
    Human
    Quelle
    • 5
    Synthetic
    Applikation
    Blocking Peptide (BP), Western Blotting (WB)
    Sequenz
    IRKLQKEQQR SKDLESRQRS LEQANRSLQL RIQELELQAQ IHGLPVPPTP
    Produktmerkmale
    This is a synthetic peptide designed for use in combination with anti-TFE3 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    TFE3 (Transcription Factor E3 (TFE3))
    Synonyme
    RCCP2 Peptide, RCCX1 Peptide, TFEA Peptide, bHLHe33 Peptide, F830016E06Rik Peptide, Tcfe3 Peptide, Tfe-3 Peptide, RGD1559642 Peptide, cb873 Peptide, zgc:109815 Peptide, transcription factor binding to IGHM enhancer 3 Peptide, transcription factor E3 Peptide, transcription factor binding to IGHM enhancer 3 S homeolog Peptide, transcription factor binding to IGHM enhancer 3a Peptide, TFE3 Peptide, Tfe3 Peptide, tfe3.S Peptide, tfe3a Peptide
    Hintergrund
    This gene encodes a basic helix-loop-helix domain-containing transcription factor that binds MUE3-type E-box sequences in the promoter of genes. The encoded protein promotes the expression of genes downstream of transforming growth factor beta (TGF-beta) signaling. This gene may be involved in chromosomal translocations in renal cell carcinomas and other cancers, resulting in the production of fusion proteins. Translocation partners include PRCC (papillary renal cell carcinoma), NONO (non-POU domain containing, octamer-binding), and ASPSCR1 (alveolar soft part sarcoma chromosome region, candidate 1), among other genes. Alternative splicing results in multiple transcript variants.

    Alias Symbols: TFEA, RCCP2, RCCX1, bHLHe33

    Protein Size: 575
    Gen-ID
    7030
    NCBI Accession
    NM_001282142, NP_001269071
    UniProt
    P19532
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