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RAS Protein Activator Like 1 (GAP1 Like) (RASAL1) (Middle Region) Peptid

RASAL1 Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN5511497
  • Target Alle RASAL1 Produkte
    RASAL1 (RAS Protein Activator Like 1 (GAP1 Like) (RASAL1))
    Protein Region
    Middle Region
    Spezies
    Human
    Quelle
    • 4
    Synthetic
    Applikation
    Blocking Peptide (BP), Western Blotting (WB)
    Sequenz
    DLGRTRRISF KGALSEEQMR ETSLGLLTGY LGPIVDAIVG SVGRCPPAMR
    Produktmerkmale
    This is a synthetic peptide designed for use in combination with anti-RASAL1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    RASAL1 (RAS Protein Activator Like 1 (GAP1 Like) (RASAL1))
    Hintergrund
    The protein encoded by this gene is member of the GAP1 family of GTPase-activating proteins. These proteins stimulate the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. This particular family member contains domains which are characteristic of the GAP1 subfamily of RasGAP proteins but, in contrast to the other GAP1 family members, this protein is strongly and selectively expressed in endocrine tissues. Alternatively spliced transcript variants that encode different isoforms have been described.

    Alias Symbols: RASAL1,RASAL,

    Protein Size: 804
    Gen-ID
    8437
    UniProt
    O95294
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