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Peroxiredoxin 2 (PRDX2) (C-Term) Peptid

PRDX2 Reaktivität: Ratte Wirt: Synthetic BP, WB
Produktnummer ABIN5511454

Kurzübersicht für Peroxiredoxin 2 (PRDX2) (C-Term) Peptid (ABIN5511454)

Target

Peroxiredoxin 2 (PRDX2)

Spezies

Ratte

Quelle

  • 4
Synthetic

Applikation

Blocking Peptide (BP), Western Blotting (WB)
  • Protein Region

    C-Term

    Sequenz

    GRSVDEALRL VQAFQYTDEH GEVCPAGWKP GSDTIKPNVD DSKEYFSKHN

    Produktmerkmale

    This is a synthetic peptide designed for use in combination with PRDX2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • Applikationshinweise

    Optimal working dilution should be determined by the investigator.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    Peroxiredoxin 2 (PRDX2)

    Hintergrund

    This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein plays an antioxidant protective role in cells, and it may contribute to the antiviral activity of CD8(+) T-cells. The crystal structure of this protein has been resolved to 2.7 angstroms. This protein prevents hemolytic anemia from oxidative stress by stabilizing hemoglobin, thus making this gene a therapeutic target for patients with hemolytic anemia. This protein may have a proliferative effect and play a role in cancer development or progression. Related pseudogenes have been identified on chromosomes 5, 6, 10 and 13.

    Alias Symbols: PRP, TSA, PRX2, PTX1, TPX1, NKEFB, PRXII, TDPX1, NKEF-B, HEL-S-2a

    Protein Size: 198

    Gen-ID

    7001

    NCBI Accession

    XM_006255244, NP_005800

    UniProt

    A0A0G2JSH9
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