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Protein Regulator of Cytokinesis 1 (PRC1) (Middle Region) Peptid

PRC1 Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN5511453
  • Target Alle PRC1 Produkte
    PRC1 (Protein Regulator of Cytokinesis 1 (PRC1))
    Protein Region
    Middle Region
    Spezies
    Human
    Quelle
    Synthetic
    Applikation
    Blocking Peptide (BP), Western Blotting (WB)
    Sequenz
    LWEQEHSKAF MVNGQKFMEY VAEQWEMHRL EKERAKQERQ LKNKKQTETE
    Produktmerkmale
    This is a synthetic peptide designed for use in combination with anti-PRC1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    PRC1 (Protein Regulator of Cytokinesis 1 (PRC1))
    Synonyme
    cb212 Peptide, prc1 Peptide, prc1l Peptide, zgc:55982 Peptide, zgc:86918 Peptide, MGC68845 Peptide, zgc:55664 Peptide, ase1 Peptide, ASE1 Peptide, D7Ertd348e Peptide, protein regulator of cytokinesis 1 Peptide, protein regulator of cytokinesis 1a Peptide, protein regulator of cytokinesis 1 S homeolog Peptide, protein regulator of cytokinesis 1b Peptide, PRC1 Peptide, prc1a Peptide, prc1.S Peptide, prc1b Peptide, CNC07120 Peptide, prc1 Peptide, Prc1 Peptide
    Hintergrund
    This gene encodes a protein that is involved in cytokinesis. The protein is present at high levels during the S and G2/M phases of mitosis but its levels drop dramatically when the cell exits mitosis and enters the G1 phase. It is located in the nucleus during interphase, becomes associated with mitotic spindles in a highly dynamic manner during mitosis, and localizes to the cell mid-body during cytokinesis. This protein has been shown to be a substrate of several cyclin-dependent kinases (CDKs). It is necessary for polarizing parallel microtubules and concentrating the factors responsible for contractile ring assembly. Alternative splicing results in multiple transcript variants.

    Alias Symbols: ASE1

    Protein Size: 195
    Gen-ID
    9055
    NCBI Accession
    NP_001254509
    UniProt
    H0YL53
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