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Protein Regulator of Cytokinesis 1 (PRC1) (Middle Region) Peptid

PRC1 Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN5511453

Kurzübersicht für Protein Regulator of Cytokinesis 1 (PRC1) (Middle Region) Peptid (ABIN5511453)

Target

PRC1 (Protein Regulator of Cytokinesis 1 (PRC1))

Spezies

Human

Quelle

Synthetic

Applikation

Blocking Peptide (BP), Western Blotting (WB)
  • Protein Region

    Middle Region

    Sequenz

    LWEQEHSKAF MVNGQKFMEY VAEQWEMHRL EKERAKQERQ LKNKKQTETE

    Produktmerkmale

    This is a synthetic peptide designed for use in combination with anti-PRC1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • Applikationshinweise

    Optimal working dilution should be determined by the investigator.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    PRC1 (Protein Regulator of Cytokinesis 1 (PRC1))

    Hintergrund

    This gene encodes a protein that is involved in cytokinesis. The protein is present at high levels during the S and G2/M phases of mitosis but its levels drop dramatically when the cell exits mitosis and enters the G1 phase. It is located in the nucleus during interphase, becomes associated with mitotic spindles in a highly dynamic manner during mitosis, and localizes to the cell mid-body during cytokinesis. This protein has been shown to be a substrate of several cyclin-dependent kinases (CDKs). It is necessary for polarizing parallel microtubules and concentrating the factors responsible for contractile ring assembly. Alternative splicing results in multiple transcript variants.

    Alias Symbols: ASE1

    Protein Size: 195

    Gen-ID

    9055

    NCBI Accession

    NP_001254509

    UniProt

    H0YL53
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