Paraoxonase 2 (PON2) (Middle Region) Peptid
PON2
Reaktivität: Human
Wirt: Synthetic
BP, WB
Produktnummer ABIN5511445
Kurzübersicht für Paraoxonase 2 (PON2) (Middle Region) Peptid (ABIN5511445)
Target
PON2
(Paraoxonase 2 (PON2))
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Sequenz
- LDTLVDNLSI DPSSGDIWVG CHPNGQKLFV YDPNNPPSSE VLRIQNILCE
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti- PON2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- PON2 (Paraoxonase 2 (PON2))
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Hintergrund
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This gene encodes a member of the paraoxonase gene family, which includes three known members located adjacent to each other on the long arm of chromosome 7. The encoded protein is ubiquitously expressed in human tissues, membrane-bound, and may act as a cellular antioxidant, protecting cells from oxidative stress. Hydrolytic activity against acylhomoserine lactones, important bacterial quorum-sensing mediators, suggests the encoded protein may also play a role in defense responses to pathogenic bacteria. Mutations in this gene may be associated with vascular disease and a number of quantitative phenotypes related to diabetes. Alternatively spliced transcript variants encoding different isoforms have been described.
Protein Size: 354 -
Gen-ID
- 5445
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NCBI Accession
- NM_000305, NP_000296
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UniProt
- Q15165
Target
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