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Paired Box 3 (PAX3) (C-Term) Peptid

PAX3 Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN5511428

Kurzübersicht für Paired Box 3 (PAX3) (C-Term) Peptid (ABIN5511428)

Target

Paired Box 3 (PAX3)

Spezies

Human

Quelle

  • 8
Synthetic

Applikation

Blocking Peptide (BP), Western Blotting (WB)
  • Protein Region

    C-Term

    Sequenz

    SSAYCLPSTR HGFSSYTDSF VPPSGPSNPM NPTIGNGLSP QVPFIISSQI

    Produktmerkmale

    This is a synthetic peptide designed for use in combination with anti-PAX3 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • Applikationshinweise

    Optimal working dilution should be determined by the investigator.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    Paired Box 3 (PAX3)

    Hintergrund

    This gene is a member of the paired box (PAX) family of transcription factors. Members of the PAX family typically contain a paired box domain and a paired-type homeodomain. These genes play critical roles during fetal development. Mutations in paired box gene 3 are associated with Waardenburg syndrome, craniofacial-deafness-hand syndrome, and alveolar rhabdomyosarcoma. The translocation t(2,13)(q35,q14), which represents a fusion between PAX3 and the forkhead gene, is a frequent finding in alveolar rhabdomyosarcoma. Alternative splicing results in transcripts encoding isoforms with different C-termini.

    Alias Symbols: PAX3,HUP2,

    Protein Size: 403

    Gen-ID

    5077

    NCBI Accession

    NP_852126
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