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OTU Domain, Ubiquitin Aldehyde Binding 1 (OTUB1) Peptid

OTUB1 Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN5511414
  • Target Alle OTUB1 Produkte
    OTUB1 (OTU Domain, Ubiquitin Aldehyde Binding 1 (OTUB1))
    Spezies
    Human
    Quelle
    • 6
    Synthetic
    Applikation
    Blocking Peptide (BP), Western Blotting (WB)
    Produktmerkmale
    This is a synthetic peptide designed for use in combination with anti-OTUB1 antibody (Catalog #: ARP59280_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    OTUB1 (OTU Domain, Ubiquitin Aldehyde Binding 1 (OTUB1))
    Hintergrund
    The product of this gene is a member of the OTU (ovarian tumor) superfamily of predicted cysteine proteases. The encoded protein is a highly specific ubiquitin iso-peptidase, and cleaves ubiquitin from branched poly-ubiquitin chains but not from ubiquitinated substrates. It interacts with another ubiquitin protease and an E3 ubiquitin ligase that inhibits cytokine gene transcription in the immune system. It is proposed to function in specific ubiquitin-dependent pathways, possibly by providing an editing function for polyubiquitin chain growth. Alternative splicing results in multiple transcript variants.

    Alias Symbols: OTB1, OTU1

    Protein Size: 271
    Molekulargewicht
    29 kDa
    Gen-ID
    55611
    NCBI Accession
    NP_060140
    UniProt
    Q96FW1
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