OTU Domain, Ubiquitin Aldehyde Binding 1 (OTUB1) Peptid
OTUB1
Reaktivität: Human
Wirt: Synthetic
BP, WB
Produktnummer ABIN5511414
Kurzübersicht für OTU Domain, Ubiquitin Aldehyde Binding 1 (OTUB1) Peptid (ABIN5511414)
Target
OTUB1
(OTU Domain, Ubiquitin Aldehyde Binding 1 (OTUB1))
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-OTUB1 antibody (Catalog #: ARP59280_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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OTU Domain, Ubiquitin Aldehyde Binding 1 (OTUB1) peptide
OTUB1 Reaktivität: Human, Maus, Rind (Kuh), Ratte Wirt: Synthetic BP, Imm
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- OTUB1 (OTU Domain, Ubiquitin Aldehyde Binding 1 (OTUB1))
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Hintergrund
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The product of this gene is a member of the OTU (ovarian tumor) superfamily of predicted cysteine proteases. The encoded protein is a highly specific ubiquitin iso-peptidase, and cleaves ubiquitin from branched poly-ubiquitin chains but not from ubiquitinated substrates. It interacts with another ubiquitin protease and an E3 ubiquitin ligase that inhibits cytokine gene transcription in the immune system. It is proposed to function in specific ubiquitin-dependent pathways, possibly by providing an editing function for polyubiquitin chain growth. Alternative splicing results in multiple transcript variants.
Alias Symbols: OTB1, OTU1
Protein Size: 271 -
Molekulargewicht
- 29 kDa
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Gen-ID
- 55611
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NCBI Accession
- NP_060140
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UniProt
- Q96FW1
Target
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