Neuronal Pentraxin II (NPTX2) (Middle Region) Peptid
NPTX2
Reaktivität: Human
Wirt: Synthetic
BP, WB
Produktnummer ABIN5511396
Kurzübersicht für Neuronal Pentraxin II (NPTX2) (Middle Region) Peptid (ABIN5511396)
Target
NPTX2
(Neuronal Pentraxin II (NPTX2))
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Sequenz
- GAQREAIREL TGKLARCEGL AGGKARGAGA TGKDTMGDLP RDPGHVVEQL
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti- NPTX2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- NPTX2 (Neuronal Pentraxin II (NPTX2))
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Hintergrund
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This gene encodes a member of the family of neuronal petraxins, synaptic proteins that are related to C-reactive protein. This protein is involved in excitatory synapse formation. It also plays a role in clustering of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA)-type glutamate receptors at established synapses, resulting in non-apoptotic cell death of dopaminergic nerve cells. Up-regulation of this gene in Parkinson disease (PD) tissues suggests that the protein may be involved in the pathology of PD.
Alias Symbols: NP2, NARP, NP-II
Protein Size: 431 -
Gen-ID
- 4885
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NCBI Accession
- NM_002523, NP_002514
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UniProt
- P47972
Target
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