MyoD Family Inhibitor (MDFI) (Middle Region) Peptid
MDFI
Reaktivität: Human
Wirt: Synthetic
BP, WB
Produktnummer ABIN5511381
Kurzübersicht für MyoD Family Inhibitor (MDFI) (Middle Region) Peptid (ABIN5511381)
Target
MDFI
(MyoD Family Inhibitor (MDFI))
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Sequenz
- AVTCQPQGNP LGCTPLLPND SGHPSELGGT RRAGNGALGG PKAHRKLQTH
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-MDFI Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- MDFI (MyoD Family Inhibitor (MDFI))
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Hintergrund
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This protein is a transcription factor that negatively regulates other myogenic family proteins. Studies of the mouse homolog, I-mf, show that it interferes with myogenic factor function by masking nuclear localization signals and preventing DNA binding. Knockout mouse studies show defects in the formation of vertebrae and ribs that also involve cartilage formation in these structures.
Alias Symbols: MDFI,
Protein Size: 246 -
Gen-ID
- 4188
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NCBI Accession
- NP_005577
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UniProt
- Q99750
Target
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