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MyoD Family Inhibitor (MDFI) (Middle Region) Peptid

MDFI Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN5511381
  • Target Alle MDFI Produkte
    MDFI (MyoD Family Inhibitor (MDFI))
    Protein Region
    Middle Region
    Spezies
    Human
    Quelle
    • 4
    Synthetic
    Applikation
    Blocking Peptide (BP), Western Blotting (WB)
    Sequenz
    AVTCQPQGNP LGCTPLLPND SGHPSELGGT RRAGNGALGG PKAHRKLQTH
    Produktmerkmale
    This is a synthetic peptide designed for use in combination with anti-MDFI Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    MDFI (MyoD Family Inhibitor (MDFI))
    Hintergrund
    This protein is a transcription factor that negatively regulates other myogenic family proteins. Studies of the mouse homolog, I-mf, show that it interferes with myogenic factor function by masking nuclear localization signals and preventing DNA binding. Knockout mouse studies show defects in the formation of vertebrae and ribs that also involve cartilage formation in these structures.

    Alias Symbols: MDFI,

    Protein Size: 246
    Gen-ID
    4188
    NCBI Accession
    NP_005577
    UniProt
    Q99750
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