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Uncoupling Protein 3 (Mitochondrial, Proton Carrier) (UCP3) (Middle Region) Peptid

UCP3 Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN5511377
  • Target Alle UCP3 Produkte
    UCP3 (Uncoupling Protein 3 (Mitochondrial, Proton Carrier) (UCP3))
    Protein Region
    Middle Region
    Spezies
    Human
    Quelle
    • 5
    Synthetic
    Applikation
    Blocking Peptide (BP), Western Blotting (WB)
    Sequenz
    CTTGAMAVTC AQPTDVVKVR FQASIHLGPS RSDRKYSGTM DAYRTIAREE
    Produktmerkmale
    This is a synthetic peptide designed for use in combination with anti- UCP3 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    UCP3 (Uncoupling Protein 3 (Mitochondrial, Proton Carrier) (UCP3))
    Synonyme
    UCP Peptide, UCP3 Peptide, slc25a9 Peptide, LOC100229080 Peptide, SLC25A9 Peptide, AI645527 Peptide, Slc25a9 Peptide, UCP-3 Peptide, uncoupling protein 3 Peptide, uncoupling protein Peptide, mitochondrial uncoupling protein 3 Peptide, uncoupling protein 3 (mitochondrial, proton carrier) S homeolog Peptide, uncoupling protein 3 (mitochondrial, proton carrier) Peptide, UCP3 Peptide, UCP1 Peptide, UCP2 Peptide, LOC100303663 Peptide, ucp3.S Peptide, LOC100229080 Peptide, Ucp3 Peptide
    Hintergrund
    Mitochondrial uncoupling proteins (UCP) are members of the larger family of mitochondrial anion carrier proteins (MACP). UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. The different UCPs have tissue-specific expression, this gene is primarily expressed in skeletal muscle. This gene's protein product is postulated to protect mitochondria against lipid-induced oxidative stress. Expression levels of this gene increase when fatty acid supplies to mitochondria exceed their oxidation capacity and the protein enables the export of fatty acids from mitochondria. UCPs contain the three solcar protein domains typically found in MACPs. Two splice variants have been found for this gene.

    Alias Symbols: SLC25A9

    Protein Size: 275
    Gen-ID
    7352
    NCBI Accession
    NM_003356, NP_003347
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