Uncoupling Protein 3 (Mitochondrial, Proton Carrier) (UCP3) (Middle Region) Peptid
UCP3
Reaktivität: Human
Wirt: Synthetic
BP, WB
Produktnummer ABIN5511377
Kurzübersicht für Uncoupling Protein 3 (Mitochondrial, Proton Carrier) (UCP3) (Middle Region) Peptid (ABIN5511377)
Target
UCP3
(Uncoupling Protein 3 (Mitochondrial, Proton Carrier) (UCP3))
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Sequenz
- CTTGAMAVTC AQPTDVVKVR FQASIHLGPS RSDRKYSGTM DAYRTIAREE
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti- UCP3 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- UCP3 (Uncoupling Protein 3 (Mitochondrial, Proton Carrier) (UCP3))
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Hintergrund
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Mitochondrial uncoupling proteins (UCP) are members of the larger family of mitochondrial anion carrier proteins (MACP). UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. The different UCPs have tissue-specific expression, this gene is primarily expressed in skeletal muscle. This gene's protein product is postulated to protect mitochondria against lipid-induced oxidative stress. Expression levels of this gene increase when fatty acid supplies to mitochondria exceed their oxidation capacity and the protein enables the export of fatty acids from mitochondria. UCPs contain the three solcar protein domains typically found in MACPs. Two splice variants have been found for this gene.
Alias Symbols: SLC25A9
Protein Size: 275 -
Gen-ID
- 7352
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NCBI Accession
- NM_003356, NP_003347
Target
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