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Interleukin 1 Receptor Accessory Protein (IL1RAP) (C-Term) Peptid

IL1RAP Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN5511305

Kurzübersicht für Interleukin 1 Receptor Accessory Protein (IL1RAP) (C-Term) Peptid (ABIN5511305)

Target

IL1RAP (Interleukin 1 Receptor Accessory Protein (IL1RAP))

Spezies

Human

Quelle

  • 1
Synthetic

Applikation

Blocking Peptide (BP), Western Blotting (WB)
  • Protein Region

    C-Term

    Sequenz

    LVQYKAVKET KVKELKRAKT VLTVIKWKGE KSKYPQGRFW KQLQVAMPVK

    Produktmerkmale

    This is a synthetic peptide designed for use in combination with anti-IL1RAP Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • Applikationshinweise

    Optimal working dilution should be determined by the investigator.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    IL1RAP (Interleukin 1 Receptor Accessory Protein (IL1RAP))

    Hintergrund

    Interleukin 1 induces synthesis of acute phase and proinflammatory proteins during infection, tissue damage, or stress, by forming a complex at the cell membrane with an interleukin 1 receptor and an accessory protein. This gene encodes the interleukin 1 receptor accessory protein. The protein is a necessary part of the interleukin 1 receptor complex which initiates signalling events that result in the activation of interleukin 1-responsive genes. Alternative splicing of this gene results in two transcript variants encoding two different isoforms, one membrane-bound and one soluble. The ratio of soluble to membrane-bound forms increases during acute-phase induction or stress.

    Alias Symbols: IL1R3, C3orf13, IL-1RAcP

    Protein Size: 570

    Gen-ID

    3556

    NCBI Accession

    NM_001167928, NP_001161400

    UniProt

    Q9NPH3
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