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Heterogeneous Nuclear Ribonucleoprotein L (HNRNPL) (Middle Region) Peptid

HNRNPL Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN5511280

Kurzübersicht für Heterogeneous Nuclear Ribonucleoprotein L (HNRNPL) (Middle Region) Peptid (ABIN5511280)

Target

HNRNPL (Heterogeneous Nuclear Ribonucleoprotein L (HNRNPL))

Spezies

Human

Quelle

  • 7
Synthetic

Applikation

Blocking Peptide (BP), Western Blotting (WB)
  • Protein Region

    Middle Region

    Sequenz

    IEYAKPTRLN VFKNDQDTWD YTNPNLSGQG DPGSNPNKRQ RQPPLLGDHP

    Produktmerkmale

    This is a synthetic peptide designed for use in combination with anti-HNRPL Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • Applikationshinweise

    Optimal working dilution should be determined by the investigator.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    HNRNPL (Heterogeneous Nuclear Ribonucleoprotein L (HNRNPL))

    Hintergrund

    Heterogeneous nuclear RNAs (hnRNAs) which include mRNA precursors and mature mRNAs are associated with specific proteins to form heterogenous ribonucleoprotein (hnRNP) complexes. Heterogeneous nuclear ribonucleoprotein L is among the proteins that are stably associated with hnRNP complexes and along with other hnRNP proteins is likely to play a major role in the formation, packaging, processing, and function of mRNA. Heterogeneous nuclear ribonucleoprotein L is present in the nucleoplasm as part of the HNRP complex. HNRP proteins have also been identified outside of the nucleoplasm. Exchange of hnRNP for mRNA-binding proteins accompanies transport of mRNA from the nucleus to the cytoplasm. Since HNRP proteins have been shown to shuttle between the nucleus and the cytoplasm, it is possible that they also have cytoplasmic functions. Two transcript variants encoding different isoforms have been found for this gene.

    Alias Symbols: HNRNPL,HNRPL,P/OKcl.14,

    Protein Size: 589

    Gen-ID

    3191

    NCBI Accession

    NP_001524

    UniProt

    P14866
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