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HtrA Serine Peptidase 2 (HTRA2) (Middle Region) Peptid

HTRA2 Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN5511273

Kurzübersicht für HtrA Serine Peptidase 2 (HTRA2) (Middle Region) Peptid (ABIN5511273)

Target

HTRA2 (HtrA Serine Peptidase 2 (HTRA2))

Spezies

Human

Quelle

  • 1
Synthetic

Applikation

Blocking Peptide (BP), Western Blotting (WB)
  • Protein Region

    Middle Region

    Sequenz

    TMKVTAGISF AIPSDRLREF LHRGEKKNSS SGISGSQRRY IGVMMLTLSP

    Produktmerkmale

    This is a synthetic peptide designed for use in combination with anti-HTRA2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • Applikationshinweise

    Optimal working dilution should be determined by the investigator.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    HTRA2 (HtrA Serine Peptidase 2 (HTRA2))

    Hintergrund

    This gene encodes a serine protease. The protein has been localized in the endoplasmic reticulum and interacts with an alternatively spliced form of mitogen-activated protein kinase 14. The protein has also been localized to the mitochondria with release to the cytosol following apoptotic stimulus. The protein is thought to induce apoptosis by binding the apoptosis inhibitory protein baculoviral IAP repeat-containing 4. Nuclear localization of this protein has also been observed. Alternate splicing of this gene results in two transcript variants encoding different isoforms. Additional transcript variants have been described, but their full-length sequences have not been determined.

    Alias Symbols: OMI, PARK13, PRSS25

    Protein Size: 361

    Gen-ID

    27429

    NCBI Accession

    NM_013247, NP_037379
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