HtrA Serine Peptidase 2 (HTRA2) (Middle Region) Peptid
HTRA2
Reaktivität: Human
Wirt: Synthetic
BP, WB
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- Target Alle HTRA2 Produkte
- HTRA2 (HtrA Serine Peptidase 2 (HTRA2))
- Protein Region
- Middle Region
- Spezies
- Human
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Quelle
- Synthetic
- Applikation
- Blocking Peptide (BP), Western Blotting (WB)
- Sequenz
- TMKVTAGISF AIPSDRLREF LHRGEKKNSS SGISGSQRRY IGVMMLTLSP
- Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-HTRA2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- HTRA2 (HtrA Serine Peptidase 2 (HTRA2))
- Hintergrund
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This gene encodes a serine protease. The protein has been localized in the endoplasmic reticulum and interacts with an alternatively spliced form of mitogen-activated protein kinase 14. The protein has also been localized to the mitochondria with release to the cytosol following apoptotic stimulus. The protein is thought to induce apoptosis by binding the apoptosis inhibitory protein baculoviral IAP repeat-containing 4. Nuclear localization of this protein has also been observed. Alternate splicing of this gene results in two transcript variants encoding different isoforms. Additional transcript variants have been described, but their full-length sequences have not been determined.
Alias Symbols: OMI, PARK13, PRSS25
Protein Size: 361 - Gen-ID
- 27429
- NCBI Accession
- NM_013247, NP_037379
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