Tripeptidyl Peptidase I (TPP1) (C-Term) Peptid
TPP1
Reaktivität: Human
Wirt: Synthetic
BP, WB
Produktnummer ABIN5511099
Kurzübersicht für Tripeptidyl Peptidase I (TPP1) (C-Term) Peptid (ABIN5511099)
Target
TPP1
(Tripeptidyl Peptidase I (TPP1))
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
-
-
Protein Region
- C-Term
-
Sequenz
- QHGAGLFDVT RGCHESCLDE EVEGQGFCSG PGWDPVTGWG TPNFPALLKT
-
Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti- TPP1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
-
-
-
-
Applikationshinweise
- Optimal working dilution should be determined by the investigator.
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Lyophilized
-
Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
-
- TPP1 (Tripeptidyl Peptidase I (TPP1))
-
Hintergrund
-
This gene encodes a member of the sedolisin family of serine proteases. The protease functions in the lysosome to cleave N-terminal tripeptides from substrates, and has weaker endopeptidase activity. It is synthesized as a catalytically-inactive enzyme which is activated and auto-proteolyzed upon acidification. Mutations in this gene result in late-infantile neuronal ceroid lipofuscinosis, which is associated with the failure to degrade specific neuropeptides and a subunit of ATP synthase in the lysosome.
Alias Symbols: CLN2, GIG1, LPIC, SCAR7, TPP-1
Protein Size: 563 -
Gen-ID
- 1200
-
NCBI Accession
- NM_000391, NP_000382
-
UniProt
- O14773
Target
-
Sie sind hier:
