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Sirtuin 3 (SIRT3) (N-Term) Peptid

SIRT3 Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN5511098

Kurzübersicht für Sirtuin 3 (SIRT3) (N-Term) Peptid (ABIN5511098)

Target

SIRT3 (Sirtuin 3 (SIRT3))

Spezies

Human

Quelle

  • 8
Synthetic

Applikation

Blocking Peptide (BP), Western Blotting (WB)
  • Protein Region

    N-Term

    Sequenz

    AAAPSFFFSS IKGGRRSISF SVGASSVVGS GGSSDKGKLS LQDVAELIRA

    Produktmerkmale

    This is a synthetic peptide designed for use in combination with anti-SIR3 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • Applikationshinweise

    Optimal working dilution should be determined by the investigator.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    SIRT3 (Sirtuin 3 (SIRT3))

    Hintergrund

    This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined, however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Two alternatively spliced transcript variants that encode different proteins have been described for this gene.

    Alias Symbols: SIRT3,SIR2L3,

    Protein Size: 399

    Gen-ID

    23410

    NCBI Accession

    NP_036371

    UniProt

    Q9NTG7
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