Cathepsin F (CTSF) (C-Term) Peptid
CTSF
Reaktivität: Human
Wirt: Synthetic
BP, WB
Produktnummer ABIN5511087
Kurzübersicht für Cathepsin F (CTSF) (C-Term) Peptid (ABIN5511087)
Target
Cathepsin F (CTSF)
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
-
-
Protein Region
- C-Term
-
Sequenz
- RPLCSPWLID HAVLLVGYGN RSDVPFWAIK NSWGTDWGEK GYYYLHRGSG
-
Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti- CTSF Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
-
-
Cathepsin F (CTSF) peptide
CTSF Reaktivität: Human, Maus, Ratte, Hund Wirt: Synthetic BP, Imm
-
-
Applikationshinweise
- Optimal working dilution should be determined by the investigator.
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Lyophilized
-
Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
-
- Cathepsin F (CTSF)
-
Hintergrund
-
Cathepsins are papain family cysteine proteinases that represent a major component of the lysosomal proteolytic system. Cathepsins generally contain a signal sequence, followed by a propeptide and then a catalytically active mature region. The very long (251 amino acid residues) proregion of the cathepsin F precursor contains a C-terminal domain similar to the pro-segment of cathepsin L-like enzymes, a 50-residue flexible linker peptide, and an N-terminal domain predicted to adopt a cystatin-like fold. The cathepsin F proregion is unique within the papain family cysteine proteases in that it contains this additional N-terminal segment predicted to share structural similarities with cysteine protease inhibitors of the cystatin superfamily. This cystatin-like domain contains some of the elements known to be important for inhibitory activity. CTSF encodes a predicted protein of 484 amino acids which contains a 19 residue signal peptide. Cathepsin F contains five potential N-glycosylation sites, and it may be targeted to the endosomal/lysosomal compartment via the mannose 6-phosphate receptor pathway. The cathepsin F gene is ubiquitously expressed, and it maps to chromosome 11q13, close to the gene encoding cathepsin W.
Alias Symbols: CATSF, CLN13
Protein Size: 484 -
Gen-ID
- 8722
-
NCBI Accession
- NM_003793, NP_003784
-
UniProt
- Q9UBX1
Target
-
Sie sind hier:
