Caspase Recruitment Domain Family, Member 11 (CARD11) (Middle Region) Peptid
CARD11
Reaktivität: Human
Wirt: Synthetic
BP, WB
Kurzübersicht für Caspase Recruitment Domain Family, Member 11 (CARD11) (Middle Region) Peptid (ABIN5511030)
Target
CARD11
(Caspase Recruitment Domain Family, Member 11 (CARD11))
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Sequenz
- SPRLSRASFL FGQLLQFVSR SENKYKRMNS NERVRIISGS PLGSLARSSL
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-CARD11 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Caspase Recruitment Domain Family, Member 11 (CARD11) peptide
CARD11 Reaktivität: Human, Maus, Rind (Kuh), Hund Wirt: Synthetic BP, Imm
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- CARD11 (Caspase Recruitment Domain Family, Member 11 (CARD11))
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Hintergrund
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The protein encoded by this gene belongs to the membrane-associated guanylate kinase (MAGUK) family, a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane. This protein is also a member of the CARD protein family, which is defined by carrying a characteristic caspase-associated recruitment domain (CARD). This protein has a domain structure similar to that of CARD14 protein. The CARD domains of both proteins have been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. When expressed in cells, this protein activated NF-kappaB and induced the phosphorylation of BCL10.
Alias Symbols: PPBL, BENTA, BIMP3, IMD11, CARMA1
Protein Size: 1171 -
Gen-ID
- 84433
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NCBI Accession
- NM_032415, NP_115791
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UniProt
- Q8TES3
Target
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