Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

Bone Morphogenetic Protein Receptor 1A (BMPR1A) (N-Term) Peptid

BMPR1A Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN5510994
  • Target Alle BMPR1A Produkte
    BMPR1A (Bone Morphogenetic Protein Receptor 1A (BMPR1A))
    Protein Region
    N-Term
    Spezies
    Human
    Quelle
    • 4
    Synthetic
    Applikation
    Blocking Peptide (BP), Western Blotting (WB)
    Sequenz
    GMKSDSDQKK SENGVTLAPE DTLPFLKCYC SGHCPDDAIN NTCITNGHCF
    Produktmerkmale
    This is a synthetic peptide designed for use in combination with anti-BMPR1A Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    BMPR1A (Bone Morphogenetic Protein Receptor 1A (BMPR1A))
    Hintergrund
    The bone morphogenetic protein (BMP) receptors are a family of transmembrane serine/threonine kinases that include the type I receptors BMPR1A and BMPR1B and the type II receptor BMPR2. These receptors are also closely related to the activin receptors, ACVR1 and ACVR2. The ligands of these receptors are members of the TGF-beta superfamily. TGF-betas and activins transduce their signals through the formation of heteromeric complexes with 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding.

    Alias Symbols: BMPR1A,ACVRLK3,ALK3,

    Protein Size: 532
    Gen-ID
    657
    NCBI Accession
    XP_005270121
    UniProt
    P36894
Sie sind hier:
Kundenservice