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Amyloid beta (Abeta) (AA 1-40) Peptid

Abeta
Produktnummer ABIN399125

Kurzübersicht für Amyloid beta (Abeta) (AA 1-40) Peptid (ABIN399125)

Target

beta Amyloid (Abeta) (Amyloid beta (Abeta))
  • Protein Region

    AA 1-40

    Reinheit

    > 95 %
  • Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Lagerung

    -20 °C
  • Target

    beta Amyloid (Abeta) (Amyloid beta (Abeta))

    Hintergrund

    Beta-amyloid peptide (beta-APP) is a 40-residue peptide implicated in the pathogenesis of Alzheimer's disease (AD) and aged Down's Syndrome, which is promoted by the acquisition of an additional copy of chromosome 21. The peptide is a proteolytic product of the much larger amyloid precursor protein (APP) encoded by a gene on chromosome 21. The peptide comprises a large extracellular N-terminal domain and a short hydrophobic membrane-spanning domain, followed by a short C-terminal region. Beta-APP both precedes and forms part of the transmembrane region.

    CAS-Nummer

    131438-79-4
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