Arachidonate 5-Lipoxygenase-Activating Protein (ALOX5AP) Peptid
ALOX5AP
Reaktivität: Human
Wirt: Kaninchen
BP
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- Target Alle ALOX5AP Produkte
- ALOX5AP (Arachidonate 5-Lipoxygenase-Activating Protein (ALOX5AP))
- Spezies
- Human
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Quelle
- Kaninchen
- Applikation
- Blocking Peptide (BP)
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Lagerung
- -80 °C
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- Target
- ALOX5AP (Arachidonate 5-Lipoxygenase-Activating Protein (ALOX5AP))
- Hintergrund
- Seems to be required for the activation of 5-LO (5-lipoxygenase). Could play an essential role in the transfer of arachidonic acid to 5-LO. Binds to MK-886, a compound that blocks the biosynthesis of leukotrienes. Genetic variations in FLAP may be a cause of susceptibility to ischemic stroke [MIM:601367], also known as cerebrovascular accident or cerebral infarction. A stroke is an acute neurologic event leading to death of neural tissue of the brain and resulting in loss of motor, sensory and/or cognitive function. Ischemic strokes, resulting from vascular occlusion, is considered to be a highly complex disease consisting of a group of heterogeneous disorders with multiple genetic and environmental risk factors.
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