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Arachidonate 5-Lipoxygenase-Activating Protein (ALOX5AP) Peptid

ALOX5AP Reaktivität: Human Wirt: Kaninchen BP

Produktnummer ABIN2763850

Kurzübersicht für Arachidonate 5-Lipoxygenase-Activating Protein (ALOX5AP) Peptid (ABIN2763850)

Target

ALOX5AP (Arachidonate 5-Lipoxygenase-Activating Protein (ALOX5AP))

Spezies

Human

Quelle

Kaninchen

Applikation

Blocking Peptide (BP)

Arachidonate 5-Lipoxygenase-Activating Protein (ALOX5AP) (C-Term) peptide
ALOX5AP Reaktivität: Human Wirt: Synthetic BP, Imm

Arachidonate 5-Lipoxygenase-Activating Protein (ALOX5AP) (Internal Region) peptide
ALOX5AP Reaktivität: Human, Hund Wirt: Synthetic BP, Imm

Arachidonate 5-Lipoxygenase-Activating Protein (ALOX5AP) (Intermediate Domain) peptide
ALOX5AP Reaktivität: Human Wirt: Synthetic BP, BI

Arachidonate 5-Lipoxygenase-Activating Protein (ALOX5AP) (C-Term) peptide
ALOX5AP Reaktivität: Human Wirt: Synthetic BP, BI

Beschränkungen

Nur für Forschungszwecke einsetzbar
Lagerung

-80 °C
Target

ALOX5AP (Arachidonate 5-Lipoxygenase-Activating Protein (ALOX5AP))

Hintergrund

Seems to be required for the activation of 5-LO (5-lipoxygenase). Could play an essential role in the transfer of arachidonic acid to 5-LO. Binds to MK-886, a compound that blocks the biosynthesis of leukotrienes. Genetic variations in FLAP may be a cause of susceptibility to ischemic stroke [MIM:601367], also known as cerebrovascular accident or cerebral infarction. A stroke is an acute neurologic event leading to death of neural tissue of the brain and resulting in loss of motor, sensory and/or cognitive function. Ischemic strokes, resulting from vascular occlusion, is considered to be a highly complex disease consisting of a group of heterogeneous disorders with multiple genetic and environmental risk factors.

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