F-Box and WD Repeat Domain Containing 7 (FBXW7) Peptid
Kurzübersicht für F-Box and WD Repeat Domain Containing 7 (FBXW7) Peptid (ABIN2763846)
Target
Spezies
Quelle
Applikation
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Lagerung
- -80 °C
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- FBXW7 (F-Box and WD Repeat Domain Containing 7 (FBXW7))
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Hintergrund
- Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Probably recognizes and binds to phosphorylated target proteins. Involved in the degradation of cyclin E, NOTCH1 released notch intracellular domain (NICD), and probably PSEN1.
Target
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