Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

F-Box and WD Repeat Domain Containing 7 (FBXW7) Peptid

FBXW7 Reaktivität: Human Wirt: Kaninchen BP
Produktnummer ABIN2763846

Kurzübersicht für F-Box and WD Repeat Domain Containing 7 (FBXW7) Peptid (ABIN2763846)

Target

FBXW7 (F-Box and WD Repeat Domain Containing 7 (FBXW7))

Spezies

Human

Quelle

  • 3
Kaninchen

Applikation

Blocking Peptide (BP)
  • Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Lagerung

    -80 °C
  • Target

    FBXW7 (F-Box and WD Repeat Domain Containing 7 (FBXW7))

    Hintergrund

    Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Probably recognizes and binds to phosphorylated target proteins. Involved in the degradation of cyclin E, NOTCH1 released notch intracellular domain (NICD), and probably PSEN1.
Sie sind hier:
Chat with us!