Ring Finger Protein 216 (RNF216) (N-Term) Peptid
RNF216
Reaktivität: Human, Maus
Wirt: Synthetic
BP, WB
Produktnummer ABIN2185638
Kurzübersicht für Ring Finger Protein 216 (RNF216) (N-Term) Peptid (ABIN2185638)
Target
RNF216
(Ring Finger Protein 216 (RNF216))
Spezies
Human, Maus
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
-
-
Protein Region
- N-Term
-
Sequenz
- IVNPRLEQKV IILGENGLLF PESEPLEVQN QSSEDSETEL LSNPGEPAAS
-
Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-Rnf216 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
-
Aufreinigung
- Purified
-
-
-
-
Applikationshinweise
- Optimal working dilution should be determined by the investigator.
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Lyophilized
-
Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
-
Konzentration
- 1 mg/mL
-
Buffer
- Final peptide concentration is 1 mg/mL in PBS.
-
Handhabung
- Avoid repeat freeze-thaw cycles.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
-
- RNF216 (Ring Finger Protein 216 (RNF216))
-
Hintergrund
-
Rnf216 acts as an E3 ubiquitin ligase, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and then transfers it to substrates promoting their degradation by the proteasome. It promotes degradation of TRAF3, TLR4 and TLR9. It contributes to the regulation of antiviral responses. It down-regulates activation of NF-kappa-B, IRF3 activation and IFNB production and promotes TNF and RIP mediated apoptosis.
Protein Size: 853 -
Molekulargewicht
- 93 kDa
-
Gen-ID
- 108086
-
UniProt
- P58283
Target
-
Sie sind hier:
