Folliculogenesis Specific Basic Helix-Loop-Helix (FIGLA) (C-Term) Peptid
FIGLA
Reaktivität: Human, Maus
Wirt: Synthetic
BP, WB
Produktnummer ABIN2185022
Kurzübersicht für Folliculogenesis Specific Basic Helix-Loop-Helix (FIGLA) (C-Term) Peptid (ABIN2185022)
Target
FIGLA
(Folliculogenesis Specific Basic Helix-Loop-Helix (FIGLA))
Spezies
Human, Maus
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- C-Term
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Sequenz
- SSTRELLGNA TQPTSCASGL KKEEEGPWAY AGHSEPLYSY HQSTVPETRS
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-Figla Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Aufreinigung
- Purified
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Konzentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handhabung
- Avoid repeat freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- FIGLA (Folliculogenesis Specific Basic Helix-Loop-Helix (FIGLA))
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Hintergrund
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Figla is a germ-line specific transcription factor implicated in postnatal oocyte-specific gene expression. It plays a key regulatory role in the expression of multiple oocyte-specific genes, including those that initiate folliculogenesis and those that encode the zona pellucida (ZP1, ZP2 and ZP3) required for fertilization and early embryonic survival. It is essential for oocytes to survive and form primordial follicles. The persistence of FIGLA in adult females suggests that it may regulate additional pathways that are essential for normal ovarian development. Figla binds to the E-box (5'-CANNTG-3') of the ZPs (ZP1, ZP2, ZP3) promoters.
Alias Symbols: bHLHc8
Protein Size: 194 -
Molekulargewicht
- 21 kDa
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Gen-ID
- 26910
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NCBI Accession
- NM_012013, NP_036143
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UniProt
- O55208
Target
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