Diacylglycerol O-Acyltransferase 1 (DGAT1) (N-Term) Peptid
DGAT1
Reaktivität: Human, Maus
Wirt: Synthetic
BP, WB
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- Target Alle DGAT1 Produkte
- DGAT1 (Diacylglycerol O-Acyltransferase 1 (DGAT1))
- Protein Region
- N-Term
- Spezies
- Human, Maus
-
Quelle
- Synthetic
- Applikation
- Blocking Peptide (BP), Western Blotting (WB)
- Sequenz
- HRLQDSLFSS DSGFSNYRGI LNWCVVMLIL SNARLFLENL IKYGILVDPI
- Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-Dgat1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Aufreinigung
- Purified
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Diacylglycerol O-Acyltransferase 1 (DGAT1) peptide
DGAT1 Reaktivität: Human, Maus, Ratte, Hund Wirt: Synthetic BP, Imm
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Lyophilized
- Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Konzentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handhabung
- Avoid repeat freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
- Target
- DGAT1 (Diacylglycerol O-Acyltransferase 1 (DGAT1))
- Hintergrund
-
Dgat1 catalyzes the terminal and only committed step in triacylglycerol synthesis by using diacylglycerol and fatty acyl CoA as substrates. In contrast to DGAT2 it is not essential for survival. It may be involved in VLDL (very low density lipoprotein) assembly. In liver, Dgat1 plays a role in esterifying exogenous fatty acids to glycerol. It functions as the major acyl-CoA retinol acyltransferase (ARAT) in the skin, where it acts to maintain retinoid homeostasis and prevent retinoid toxicity leading to skin and hair disorders.
Alias Symbols: C75990, D15Ertd23e, Dgat
Protein Size: 498 - Molekulargewicht
- 57 kDa
- Gen-ID
- 13350
- NCBI Accession
- NM_010046, NP_034176
- UniProt
- Q9Z2A7
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