This is a synthetic peptide designed for use in combination with anti-RGS17 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
Konzentration
1 mg/mL
Buffer
Final peptide concentration is 1 mg/mL in PBS.
Handhabung
Avoid repeat freeze-thaw cycles.
Lagerung
-20 °C
Informationen zur Lagerung
For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
Target
RGS17
(Regulator of G-Protein Signaling 17 (RGS17))
Synonyme
RGS17 Peptide, zgc:92802 Peptide, MGC179306 Peptide, RGS-17 Peptide, RGSZ2 Peptide, hRGS17 Peptide, 6430507P11Rik Peptide, Rgsz2 Peptide, regulator of G protein signaling 17 Peptide, regulator of G-protein signaling 17 Peptide, RGS17 Peptide, Rgs17 Peptide, rgs17 Peptide
Hintergrund
This gene encodes a member of the regulator of G-protein signaling family. This protein contains a conserved, 120 amino acid motif called the RGS domain and a cysteine-rich region. The protein attenuates the signaling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal.