GRB2-Related Adaptor Protein (GRAP) (N-Term) Peptid
GRAP
Reaktivität: Human
Wirt: Synthetic
BP, WB
Produktnummer ABIN2184413
Kurzübersicht für GRB2-Related Adaptor Protein (GRAP) (N-Term) Peptid (ABIN2184413)
Target
GRAP
(GRB2-Related Adaptor Protein (GRAP))
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
-
-
Protein Region
- N-Term
-
Sequenz
- SDELAFNKGD TLKILNMEDD QNWYKAELRG VEGFIPKNYI RVKPHPWYSG
-
Produktmerkmale
- This is a synthetic peptide designed for use in combination with antiGRAP Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
-
Aufreinigung
- Purified
-
-
GRB2-Related Adaptor Protein (GRAP) peptide
GRAP Reaktivität: Human, Ratte, Rind (Kuh), Maus Wirt: Synthetic BP, Imm
-
-
Applikationshinweise
- Optimal working dilution should be determined by the investigator.
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Lyophilized
-
Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
-
Konzentration
- 1 mg/mL
-
Buffer
- Final peptide concentration is 1 mg/mL in PBS.
-
Handhabung
- Avoid repeat freeze-thaw cycles.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- For longer periods of storage, store at 20C. Avoid repeat freezethaw cycles.
-
-
- GRAP (GRB2-Related Adaptor Protein (GRAP))
-
Hintergrund
-
This gene encodes a member of the GRB2/Sem5/Drk family and functions as a cytoplasmic signaling protein which contains an SH2 domain flanked by two SH3 domains. The SH2 domain interacts with ligandactivated receptors for stem cell factor and erythropoietin, and facilitates the formation of a stable complex with the BCRABL oncoprotein. This protein also associates with the Ras guanine nucleotide exchange factor SOS1 (son of sevenless homolog 1) through its Nterminal SH3 domain. In general, it couples signals from receptor and cytoplasmic tyrosine kinases to the Ras signaling pathway.
Alias Symbols: -
Protein Size: 217 -
Molekulargewicht
- 25 kDa
-
Gen-ID
- 10750
-
NCBI Accession
- NM_006613, NP_006604
-
UniProt
- Q13588
Target
-
Sie sind hier:
