Coagulation Factor II (thrombin) Receptor-Like 1 (F2RL1) (C-Term) Peptid
Kurzübersicht für Coagulation Factor II (thrombin) Receptor-Like 1 (F2RL1) (C-Term) Peptid (ABIN2184390)
Target
Spezies
Quelle
Applikation
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Protein Region
- C-Term
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Sequenz
- SAYVLMIRML RSSAMDENSE KKRKRAIKLI VTVLAMYLIC FTPSNLLLVV
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-F2RL1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Aufreinigung
- Purified
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Konzentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handhabung
- Avoid repeat freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- F2RL1 (Coagulation Factor II (thrombin) Receptor-Like 1 (F2RL1))
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Hintergrund
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Coagulation factor II (thrombin) receptor-like 1 (F2RL1) is a member of the large family of 7-transmembrane-region receptors that couple to guanosine-nucleotide-binding proteins. F2RL1 is also a member of the protease-activated receptor family. It is activated by trypsin, but not by thrombin. It is activated by proteolytic cleavage of its extracellular amino terminus. The new amino terminus functions as a tethered ligand and activates the receptor. The F2RL1 gene contains two exons and is widely expressed in human tissues. The predicted protein sequence is 83 % identical to the mouse receptor sequence.
Alias Symbols: GPR11, PAR2
Protein Size: 397 -
Molekulargewicht
- 44 kDa
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Gen-ID
- 2150
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NCBI Accession
- NM_005242, NP_005233
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UniProt
- P55085
Target
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