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Coagulation Factor II (thrombin) Receptor-Like 1 (F2RL1) (C-Term) Peptid

F2RL1 Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN2184390

Kurzübersicht für Coagulation Factor II (thrombin) Receptor-Like 1 (F2RL1) (C-Term) Peptid (ABIN2184390)

Target

F2RL1 (Coagulation Factor II (thrombin) Receptor-Like 1 (F2RL1))

Spezies

Human

Quelle

  • 3
Synthetic

Applikation

Blocking Peptide (BP), Western Blotting (WB)
  • Protein Region

    C-Term

    Sequenz

    SAYVLMIRML RSSAMDENSE KKRKRAIKLI VTVLAMYLIC FTPSNLLLVV

    Produktmerkmale

    This is a synthetic peptide designed for use in combination with anti-F2RL1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Aufreinigung

    Purified
  • Applikationshinweise

    Optimal working dilution should be determined by the investigator.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Konzentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Handhabung

    Avoid repeat freeze-thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    F2RL1 (Coagulation Factor II (thrombin) Receptor-Like 1 (F2RL1))

    Hintergrund

    Coagulation factor II (thrombin) receptor-like 1 (F2RL1) is a member of the large family of 7-transmembrane-region receptors that couple to guanosine-nucleotide-binding proteins. F2RL1 is also a member of the protease-activated receptor family. It is activated by trypsin, but not by thrombin. It is activated by proteolytic cleavage of its extracellular amino terminus. The new amino terminus functions as a tethered ligand and activates the receptor. The F2RL1 gene contains two exons and is widely expressed in human tissues. The predicted protein sequence is 83 % identical to the mouse receptor sequence.

    Alias Symbols: GPR11, PAR2

    Protein Size: 397

    Molekulargewicht

    44 kDa

    Gen-ID

    2150

    NCBI Accession

    NM_005242, NP_005233

    UniProt

    P55085
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