Unc-13 Homolog D (UNC13D) (C-Term) Peptid
UNC13D
Reaktivität: Human
Wirt: Synthetic
BP, WB
Produktnummer ABIN2184174
Kurzübersicht für Unc-13 Homolog D (UNC13D) (C-Term) Peptid (ABIN2184174)
Target
UNC13D
(Unc-13 Homolog D (UNC13D))
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
-
-
Protein Region
- C-Term
-
Sequenz
- SGSEEPGEVP QTRLPLTYPA PNGDPILQLL EGRKGDREAQ VFVRLRRHRA
-
Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-UNC13D Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
-
Aufreinigung
- Purified
-
-
-
-
Applikationshinweise
- Optimal working dilution should be determined by the investigator.
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Lyophilized
-
Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
-
Konzentration
- 1 mg/mL
-
Buffer
- Final peptide concentration is 1 mg/mL in PBS.
-
Handhabung
- Avoid repeat freeze-thaw cycles.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
-
- UNC13D (Unc-13 Homolog D (UNC13D))
-
Hintergrund
-
This gene encodes a protein that is a member of the UNC13 family, containing similar domain structure as other family members but lacking an N-terminal phorbol ester-binding C1 domain present in other Munc13 proteins. The protein appears to play a role in vesicle maturation during exocytosis and is involved in regulation of cytolytic granules secretion. Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis type 3, a genetically heterogeneous, rare autosomal recessive disorder.
Alias Symbols: FHL3, HLH3, HPLH3, Munc13-4
Protein Size: 1090 -
Molekulargewicht
- 119 kDa
-
Gen-ID
- 201294
-
NCBI Accession
- NM_199242, NP_954712
-
UniProt
- Q70J99
Target
-
Sie sind hier:
