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Corticotropin Releasing Hormone (CRH) (C-Term) Peptid

CRH Reaktivität: Human Wirt: Synthetic WB, BP
Produktnummer ABIN2184150

Kurzübersicht für Corticotropin Releasing Hormone (CRH) (C-Term) Peptid (ABIN2184150)

Target

CRH (Corticotropin Releasing Hormone (CRH))

Spezies

Human

Quelle

  • 16
Synthetic

Applikation

Western Blotting (WB), Blocking Peptide (BP)
  • Protein Region

    C-Term

    Sequenz

    GGHQEAPERE RRSEEPPISL DLTFHLLREV LEMARAEQLA QQAHSNRKLM

    Produktmerkmale

    This is a synthetic peptide designed for use in combination with anti-CRH Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Aufreinigung

    Purified
  • Applikationshinweise

    Optimal working dilution should be determined by the investigator.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Konzentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Handhabung

    Avoid repeat freeze-thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    CRH (Corticotropin Releasing Hormone (CRH))

    Hintergrund

    Corticotropin-releasing hormone is secreted by the paraventricular nucleus (PVN) of the hypothalamus in response to stress. Marked reduction in this protein has been observed in association with Alzheimer disease and autosomal recessive hypothalamic corticotropin deficiency has multiple and potentially fatal metabolic consequences including hypoglycemia and hepatitis. In addition to production in the hypothalamus, this protein is also synthesized in peripheral tissues, such as T lymphocytes and is highly expressed in the placenta. In the placenta it is a marker that determines the length of gestation and the timing of parturition and delivery. A rapid increase in circulating levels of the hormone occurs at the onset of parturition, suggesting that, in addition to its metabolic functions, this protein may act as a trigger for parturition.

    Alias Symbols: CRF

    Protein Size: 196

    Molekulargewicht

    21 kDa

    Gen-ID

    1392

    NCBI Accession

    NM_000756, NP_000747

    UniProt

    P06850
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