Deleted in Azoospermia-Like (DAZL) (C-Term) Peptid
DAZL
Reaktivität: Human
Wirt: Synthetic
BP, WB
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- Target Alle DAZL Produkte
- DAZL (Deleted in Azoospermia-Like (DAZL))
- Protein Region
- C-Term
- Spezies
- Human
-
Quelle
- Synthetic
- Applikation
- Blocking Peptide (BP), Western Blotting (WB)
- Sequenz
- PPSGNGPQKK SVDRSIQTVV SCLFNPENRL RNSVVTQDDY FKDKRVHHFR
- Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-DAZL Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Aufreinigung
- Purified
-
Deleted in Azoospermia-Like (DAZL) peptide
DAZL Reaktivität: Human, Maus, Rind (Kuh), Hund, Ratte Wirt: Synthetic BP, Imm
-
- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Lyophilized
- Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Konzentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handhabung
- Avoid repeat freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
- Target
- DAZL (Deleted in Azoospermia-Like (DAZL))
- Hintergrund
-
DAZ (Deleted in AZoospermia) is the potential RNA binding proteins that are expressed in prenatal and postnatal germ cells of males and females. DAZL is localized to the nucleus and cytoplasm of fetal germ cells and to the cytoplasm of developing oocytes. In the testis, this protein is localized to the nucleus of spermatogonia but relocates to the cytoplasm during meiosis where it persists in spermatids and spermatozoa. Transposition and amplification of the autosomal gene encoding DAZL during primate evolution gave rise to the DAZ gene cluster on the Y chromosome. Mutations in the Dazl gene have been linked to severe spermatogenic failure and infertility in males.
Alias Symbols: DAZL
Protein Size: 295 - Molekulargewicht
- 32 kDa
- Gen-ID
- 1618
- NCBI Accession
- NM_001351, NP_001342
- UniProt
- Q92904
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