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rho GDP Dissociation Inhibitor (GDI) beta (ARHGDIB) (N-Term) Peptid

ARHGDIB Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN2182046

Kurzübersicht für rho GDP Dissociation Inhibitor (GDI) beta (ARHGDIB) (N-Term) Peptid (ABIN2182046)

Target

ARHGDIB (rho GDP Dissociation Inhibitor (GDI) beta (ARHGDIB))

Spezies

Human

Quelle

  • 2
Synthetic

Applikation

Blocking Peptide (BP), Western Blotting (WB)
  • Protein Region

    N-Term

    Sequenz

    MTEKAPEPHV EEDDDDELDS KLNYKPPPQK SLKELQEMDK DDESLIKYKK

    Produktmerkmale

    This is a synthetic peptide designed for use in combination with anti-ARHGDIB Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Aufreinigung

    Purified
  • Applikationshinweise

    Optimal working dilution should be determined by the investigator.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Konzentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Handhabung

    Avoid repeat freeze-thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    ARHGDIB (rho GDP Dissociation Inhibitor (GDI) beta (ARHGDIB))

    Hintergrund

    Members of the Rho (or ARH) protein family and other Ras-related small GTP-binding proteins are involved in diverse cellular events, including cell signaling, proliferation, cytoskeletal organization, and secretion. The GTP-binding proteins are active only in the GTP-bound state. At least 3 classes of proteins tightly regulate cycling between the GTP-bound and GDP-bound states: GTPase-activating proteins (GAPs), guanine nucleotide-releasing factors (GRFs), and GDP-dissociation inhibitors (GDIs). The GDIs, including ARHGDIB, decrease the rate of GDP dissociation from Ras-like GTPases.

    Alias Symbols: D4, GDIA2, GDID4, LYGDI, Ly-GDI, RAP1GN1, RhoGDI2

    Protein Size: 201

    Molekulargewicht

    23 kDa

    Gen-ID

    397

    NCBI Accession

    NM_001175, NP_001166

    UniProt

    P52566
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