Poly (ADP-Ribose) Polymerase 2 (PARP2) (C-Term) Peptid
Kurzübersicht für Poly (ADP-Ribose) Polymerase 2 (PARP2) (C-Term) Peptid (ABIN2181971)
Target
Spezies
Quelle
Applikation
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Protein Region
- C-Term
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Sequenz
- QCNELLEANP KAEGLLQGKH STKGLGKMAP SSAHFVTLNG STVPLGPASD
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-PARP2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Aufreinigung
- Purified
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Konzentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handhabung
- Avoid repeat freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- PARP2 (Poly (ADP-Ribose) Polymerase 2 (PARP2))
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Hintergrund
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PARP2 is involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks.
Alias Symbols: ADPRT2, ADPRTL2, ADPRTL3, ARTD2, PARP-2, pADPRT-2
Protein Size: 570 -
Molekulargewicht
- 62 kDa
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Gen-ID
- 10038
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NCBI Accession
- NM_001042618, NP_001036083
Target
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