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Poly (ADP-Ribose) Polymerase 2 (PARP2) (C-Term) Peptid

PARP2 Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN2181971

Kurzübersicht für Poly (ADP-Ribose) Polymerase 2 (PARP2) (C-Term) Peptid (ABIN2181971)

Target

PARP2 (Poly (ADP-Ribose) Polymerase 2 (PARP2))

Spezies

Human

Quelle

  • 4
Synthetic

Applikation

Blocking Peptide (BP), Western Blotting (WB)
  • Protein Region

    C-Term

    Sequenz

    QCNELLEANP KAEGLLQGKH STKGLGKMAP SSAHFVTLNG STVPLGPASD

    Produktmerkmale

    This is a synthetic peptide designed for use in combination with anti-PARP2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Aufreinigung

    Purified
  • Applikationshinweise

    Optimal working dilution should be determined by the investigator.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Konzentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Handhabung

    Avoid repeat freeze-thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    PARP2 (Poly (ADP-Ribose) Polymerase 2 (PARP2))

    Hintergrund

    PARP2 is involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks.

    Alias Symbols: ADPRT2, ADPRTL2, ADPRTL3, ARTD2, PARP-2, pADPRT-2

    Protein Size: 570

    Molekulargewicht

    62 kDa

    Gen-ID

    10038

    NCBI Accession

    NM_001042618, NP_001036083
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