Amyloid beta (Abeta) (AA 1-42) Peptid
Abeta
Reaktivität: Human
Wirt: Synthetic
Produktnummer ABIN2017638
Kurzübersicht für Amyloid beta (Abeta) (AA 1-42) Peptid (ABIN2017638)
Target
beta Amyloid (Abeta)
(Amyloid beta (Abeta))
Spezies
Human
Quelle
Synthetic
-
-
Protein Region
- AA 1-42
-
Sequenz
- DAEFRHDSGY EVHHQKLVFF AEDVGSNKGA IIGLMVGGVV IA
-
Spezifität
- Formula: C203H311N55O60S1
-
Produktmerkmale
- This peptide is well suited to the quantitative determination of A 42 peptide. Alzheimer's disease (AD) is characterized by the presence of extracellular plaques and intracellular neurofibrillary tangles (NFTs) in the brain. The major protein component of these plaques is beta amyloid peptide (A), a 40- to 43- amino-acid peptide cleaved from amyloid precursor protein by secretase (BACE) and a putative (gamma) secretase. Increased release of the 'longer forms' of A peptide, A 42 and A 43, which have a greater tendency to aggregate than A 40, occurs in individuals expressing certain genetic mutations, expressing certain ApoE alleles or may other, still undiscovered factors.
-
Reinheit
- > 95 %
-
-
-
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Rekonstitution
- Insoluble in water, may be dissolved in any buffer of pH >9.
-
Lagerung
- -20 °C
-
-
- beta Amyloid (Abeta) (Amyloid beta (Abeta))
-
Molekulargewicht
- 4514.100 kDa
Target
-
Sie sind hier:
