Eukaryotic Translation Initiation Factor 6 (EIF6) (C-Term) Peptid
EIF6
Reaktivität: Human
Wirt: Synthetic
BP, WB
Produktnummer ABIN1542402
Kurzübersicht für Eukaryotic Translation Initiation Factor 6 (EIF6) (C-Term) Peptid (ABIN1542402)
Target
EIF6
(Eukaryotic Translation Initiation Factor 6 (EIF6))
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- C-Term
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Sequenz
- QVLVGSYCVF SNQGGLVHPK TSIEDQDELS SLLQVPLVAG TVNRGSEVIA
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-EIF6 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Aufreinigung
- Purified
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Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Konzentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- EIF6 (Eukaryotic Translation Initiation Factor 6 (EIF6))
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Hintergrund
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Hemidesmosomes are structures which link the basal lamina to the intermediate filament cytoskeleton. An important functional component of hemidesmosomes is the integrin beta-4 subunit (ITGB4), a protein containing two fibronectin type III domains. The protein encoded by this gene binds to the fibronectin type III domains of ITGB4 and may help link ITGB4 to the intermediate filament cytoskeleton. The encoded protein, which is insoluble and found both in the nucleus and in the cytoplasm, can function as a translation initiation factor and prevent the association of the 40S and 60S ribosomal subunits.
Alias Symbols: 2, CAB, EIF3A, ITGB4BP, b, b(2)gcn, gcn, p27BBP, eIF-6, p27(BBP)
Protein Interaction Partner: GNB2L1,ABCF1,ACAP3,ACTG1,AKT1S1,ALDH2,C4orf27,CRELD1,ENOX1,FUNDC2,GIT1,GNB2L1,HIP1,ITGB4,KIAA1377,LRIF1,MRPS31,OFD1,OS9,PDHA1,POLA2,PRKCB,PSME1,RPL6,SEPT3,UPF3B,USP33,WFS1,XRN2,ABCF1,ACAP3,ACTG1,AKT1S1,ALDH2,ARF6,BCCIP,C4orf27,CRELD1,EIF3B,EIF3C,EIF3J,ENO
Protein Size: 245 -
Molekulargewicht
- 27 kDa
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Gen-ID
- 3692
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NCBI Accession
- NM_002212, NP_002203
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UniProt
- P56537
Target
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