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Isocitrate Dehydrogenase 3 (NAD+) beta (IDH3B) (N-Term) Peptid

IDH3B Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN1541540
150,78 €
Zzgl. Versandkosten 20,00 € und MwSt
100 μg
Lieferung nach: Deutschland
Lieferung in 15 bis 21 Werktagen

Kurzübersicht für Isocitrate Dehydrogenase 3 (NAD+) beta (IDH3B) (N-Term) Peptid (ABIN1541540)

Target

IDH3B (Isocitrate Dehydrogenase 3 (NAD+) beta (IDH3B))

Spezies

Human

Quelle

  • 8
Synthetic

Applikation

Blocking Peptide (BP), Western Blotting (WB)
  • Protein Region

    N-Term

    Sequenz

    SEVQNMASEE KLEQVLSSMK ENKVAIIGKI HTPMEYKGEL ASYDMRLRRK

    Produktmerkmale

    This is a synthetic peptide designed for use in combination with anti-IDH3B Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Aufreinigung

    Purified
  • Applikationshinweise

    Each Investigator should determine their own optimal working dilution for specific applications.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Konzentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Handhabung

    Avoid repeated freeze-thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    IDH3B (Isocitrate Dehydrogenase 3 (NAD+) beta (IDH3B))

    Hintergrund

    Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer that is composed of two alpha subunits, one beta subunit, and one gamma subunit. The protein encoded by this gene is the beta subunit of one isozyme of NAD(+)-dependent isocitrate dehydrogenase.

    Alias Symbols: FLJ11043, H-IDHB, MGC903, RP46

    Protein Size: 385

    Molekulargewicht

    42 kDa

    Gen-ID

    3420

    NCBI Accession

    NM_006899, NP_008830

    UniProt

    O43837
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