Sorting Nexin 15 (SNX15) (N-Term) Peptid
SNX15
Reaktivität: Human
Wirt: Synthetic
BP, WB
Produktnummer ABIN1541460
Kurzübersicht für Sorting Nexin 15 (SNX15) (N-Term) Peptid (ABIN1541460)
Target
SNX15
(Sorting Nexin 15 (SNX15))
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Sequenz
- RKLHGDLAYT HRNLFRRLEE FPAFPRAQVF GRFEASVIEE RRKGAEDLLR
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-SNX15 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Aufreinigung
- Purified
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Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Konzentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- SNX15 (Sorting Nexin 15 (SNX15))
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Hintergrund
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This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. Overexpression of this gene results in a decrease in the processing of insulin and hepatocyte growth factor receptors to their mature subunits. This decrease is caused by the mislocalization of furin, the endoprotease responsible for cleavage of insulin and hepatocyte growth factor receptors. This protein is involved in endosomal trafficking from the plasma membrane to recycling endosomes or the trans-Golgi network. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the upstream ADP-ribosylation factor-like 2 (ARL2) gene.
Alias Symbols: HSAF001435
Protein Size: 256 -
Molekulargewicht
- 29 kDa
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Gen-ID
- 29907
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NCBI Accession
- NM_147777, NP_680086
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UniProt
- E5KQS6
Target
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