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Spastic Paraplegia 21 (SPG21) (C-Term) Peptid

SPG21 Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN1541417
150,78 €
Zzgl. Versandkosten 20,00 € und MwSt
100 μg
Lieferung nach: Deutschland
Lieferung in 15 bis 22 Werktagen

Kurzübersicht für Spastic Paraplegia 21 (SPG21) (C-Term) Peptid (ABIN1541417)

Target

SPG21 (Spastic Paraplegia 21 (SPG21))

Spezies

Human

Quelle

  • 2
Synthetic

Applikation

Blocking Peptide (BP), Western Blotting (WB)
  • Protein Region

    C-Term

    Sequenz

    IPVTIMDVFD QSALSTEAKE EMYKLYPNAR RAHLKTGGNF PYLCRSAEVN

    Produktmerkmale

    This is a synthetic peptide designed for use in combination with anti-SPG21 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Aufreinigung

    Purified
  • Applikationshinweise

    Each Investigator should determine their own optimal working dilution for specific applications.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Konzentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Handhabung

    Avoid repeated freeze-thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    SPG21 (Spastic Paraplegia 21 (SPG21))

    Hintergrund

    The protein encoded by this gene was identified by a two-hybrid screen using CD4 as the bait. It binds to the hydrophobic C-terminal amino acids of CD4 which are involved in repression of T cell activation. The interaction with CD4 is mediated by the noncatalytic alpha/beta hydrolase fold domain of this protein. It is thus proposed that this gene product modulates the stimulatory activity of CD4. At least three different transcript variants encoding two different isoforms have been found for this gene.

    Alias Symbols: ACP33, BM-019, GL010, MASPARDIN, MAST

    Protein Size: 308

    Molekulargewicht

    35 kDa

    Gen-ID

    51324

    NCBI Accession

    NM_016630, NP_057714

    UniProt

    Q9NZD8
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