Histamine Receptor H3 (HRH3) (N-Term) Peptid
HRH3
Reaktivität: Human, Ratte
Wirt: Synthetic
BP, WB
Produktnummer ABIN1541323
Kurzübersicht für Histamine Receptor H3 (HRH3) (N-Term) Peptid (ABIN1541323)
Target
HRH3
(Histamine Receptor H3 (HRH3))
Spezies
Human, Ratte
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Sequenz
- VFNIVLISYD RFLSVTRAVS YRAQQGDTRR AVRKMALVWV LAFLLYGPAI
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-Hrh3 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Aufreinigung
- Purified
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Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Konzentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- HRH3 (Histamine Receptor H3 (HRH3))
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Hintergrund
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This gene encodes a histamine H3 receptor that belongs to the superfamily of G-protein coupled receptors. This protein functions as a presynaptic autoreceptor on histamine neurons in the brain, and a presynaptic heteroreceptor in nonhistamine-containing neurons in both the central and peripheral nervous systems. It is deemed a great target for the development of therapeutics for numerous disorders, including obesity, epilepsy, and such cognitive diseases as attention deficit hyperactivity disorder and Alzheimer's disease. Several alternatively spliced transcript variants encoding different isoforms, with different brain expression patterns and signaling properties, have been described for this gene.
Alias Symbols: -
Protein Size: 445 -
Molekulargewicht
- 48 kDa
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Gen-ID
- 85268
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NCBI Accession
- NM_053506, NP_445958
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UniProt
- Q9QYN8
Target
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