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Muscarinic Acetylcholine Receptor M1 (CHRM1) (C-Term) Peptid

CHRM1 Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN1541301

Kurzübersicht für Muscarinic Acetylcholine Receptor M1 (CHRM1) (C-Term) Peptid (ABIN1541301)

Target

CHRM1 (Muscarinic Acetylcholine Receptor M1 (CHRM1))

Spezies

Human

Quelle

  • 4
Synthetic

Applikation

Blocking Peptide (BP), Western Blotting (WB)
  • Protein Region

    C-Term

    Sequenz

    VKRPTKKGRD RAGKGQKPRG KEQLAKRKTF SLVKEKKAAR TLSAILLAFI

    Produktmerkmale

    This is a synthetic peptide designed for use in combination with anti-CHRM1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Aufreinigung

    Purified
  • Applikationshinweise

    Each Investigator should determine their own optimal working dilution for specific applications.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Konzentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Handhabung

    Avoid repeated freeze-thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    CHRM1 (Muscarinic Acetylcholine Receptor M1 (CHRM1))

    Hintergrund

    The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 1 is involved in mediation of vagally-induced bronchoconstriction and in the acid secretion of the gastrointestinal tract. The gene encoding this receptor is localized to 11q13.

    Alias Symbols: HM1, M1, M1R, MGC30125

    Protein Size: 460

    Molekulargewicht

    51 kDa

    Gen-ID

    1128

    NCBI Accession

    NM_000738, NP_000729

    UniProt

    P11229
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