Retinoblastoma Binding Protein 4 (RBBP4) (C-Term) Peptid
RBBP4
Reaktivität: Human, Maus
Wirt: Synthetic
WB, BP
Produktnummer ABIN1541206
Kurzübersicht für Retinoblastoma Binding Protein 4 (RBBP4) (C-Term) Peptid (ABIN1541206)
Target
Retinoblastoma Binding Protein 4 (RBBP4)
Spezies
Human, Maus
Quelle
Synthetic
Applikation
Western Blotting (WB), Blocking Peptide (BP)
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Protein Region
- C-Term
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Sequenz
- TAKISDFSWN PNEPWVICSV SEDNIMQVWQ MAENIYNDED PEGSVDPEGQ
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-Rbbp4 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Aufreinigung
- Purified
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Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Konzentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Retinoblastoma Binding Protein 4 (RBBP4)
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Hintergrund
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Rbbp4 is a core histone-binding subunit that may target chromatin assembly factors, chromatin remodeling factors and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA. Component of several complexes which regulate chromatin metabolism. These include the chromatin assembly factor 1 (CAF-1) complex, which is required for chromatin assembly following DNA replication and DNA repair, the core histone deacetylase (HDAC) complex, which promotes histone deacetylation and consequent transcriptional repression, the nucleosome remodeling and histone deacetylase complex (the NuRD complex), which promotes transcriptional repression by histone deacetylation and nucleosome remodeling, and the PRC2/EED-EZH2 complex, which promotes repression of homeotic genes during development, and the NURF (nucleosome remodeling factor) complex.
Alias Symbols: mRbAp48
Protein Size: 425 -
Molekulargewicht
- 47 kDa
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Gen-ID
- 19646
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NCBI Accession
- NM_009030, NP_033056
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UniProt
- Q60972
Target
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