Mucin 1 (MUC1) (C-Term) Peptid
MUC1
Reaktivität: Human
Wirt: Synthetic
BP, IHC
Produktnummer ABIN1540997
Kurzübersicht für Mucin 1 (MUC1) (C-Term) Peptid (ABIN1540997)
Target
MUC1
(Mucin 1 (MUC1))
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Immunohistochemistry (IHC)
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Protein Region
- C-Term
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Sequenz
- GCAGHCLSHC LGCLSVPPKE LRAAGHLSSP GYLPSYERVP HLPHPWALCA
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-MUC1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Aufreinigung
- Purified
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Mucin 1 (MUC1) peptide (Ovalbumin)
MUC1 Reaktivität: Human Wirt: Synthetic WB, Imm, SDS
Mucin 1 (MUC1) (AA 902-941) peptide (His tag)MUC1 Reaktivität: Human Wirt: Synthetic BP, Imm
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Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Konzentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- MUC1 (Mucin 1 (MUC1))
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Hintergrund
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This gene encodes a membrane-bound protein that is a member of the mucin family. Mucins are O-glycosylated proteins that play an essential role in forming protective mucous barriers on epithelial surfaces. These proteins also play a role in intracellular signaling. This protein is expressed on the apical surface of epithelial cells that line the mucosal surfaces of many different tissues including lung, breast stomach and pancreas. This protein is proteolytically cleaved into alpha and beta subunits that form a heterodimeric complex. The N-terminal alpha subunit functions in cell-adhesion and the C-terminal beta subunit is involved in cell signaling. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas. This gene is known to contain a highly polymorphic variable number tandem repeats (VNTR) domain. Alternate splicing results in multiple transcript variants.
Alias Symbols: CD227, EMA, H23AG, KL-6, MAM6, PEM, PEMT, PUM, MUC-1, MUC-1/X, MUC1/ZD, MUC-1/SEC
Protein Size: 158 -
Molekulargewicht
- 14 kDa
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Gen-ID
- 4582
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NCBI Accession
- NM_001044393, NP_001037858
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UniProt
- Q7Z538
Target
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