Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) (C-Term) Peptid
GAPDH
Reaktivität: Human, Maus
Wirt: Synthetic
BP, WB
Produktnummer ABIN1540981
150,78 €
Zzgl. Versandkosten 20,00 € und MwSt
100 μg
Lieferung nach:
Deutschland
Lieferung in 15 bis 22 Werktagen
Kurzübersicht für Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) (C-Term) Peptid (ABIN1540981)
Target
GAPDH
(Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH))
Spezies
Human, Maus
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- C-Term
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Sequenz
- FNSNSHSSTF DAGAGIALND NFVKLISWYD NEYGYSNRVV DLMAYMASKE
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-Gapdh Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Aufreinigung
- Purified
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Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Konzentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- GAPDH (Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH))
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Hintergrund
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Gapdh has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Gapdh also participates in nuclear events including transcription, RNA transport, DNA replication and apoptosis. Nuclear functions are probably due to the nitrosylase activity that mediates cysteine S-nitrosylation of nuclear target proteins such as SIRT1, HDAC2 and PRKDC.
Alias Symbols: Gapd, MGC102544, MGC102546, MGC103190, MGC103191, MGC105239
Protein Size: 333 -
Molekulargewicht
- 36 kDa
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Gen-ID
- 14433
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NCBI Accession
- NM_008084, NP_032110
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UniProt
- P16858
Target
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