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Pancreas Specific Transcription Factor, 1a (PTF1A) (N-Term) Peptid

PTF1A Reaktivität: Human, Maus Wirt: Synthetic BP, WB
Produktnummer ABIN1540933
  • Target Alle PTF1A Produkte
    PTF1A (Pancreas Specific Transcription Factor, 1a (PTF1A))
    Protein Region
    N-Term
    Spezies
    Human, Maus
    Quelle
    • 6
    Synthetic
    Applikation
    Blocking Peptide (BP), Western Blotting (WB)
    Sequenz
    FPSPYFDEED FFTDQSSRDP LEDSDELLGD EQAEVEFLSH QLHEYCYRDG
    Produktmerkmale
    This is a synthetic peptide designed for use in combination with anti-Ptf1a Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Aufreinigung
    Purified
  • Applikationshinweise
    Each Investigator should determine their own optimal working dilution for specific applications.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Konzentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    PTF1A (Pancreas Specific Transcription Factor, 1a (PTF1A))
    Synonyme
    PTF1A Peptide, PTF1 Peptide, si:zc142h2.2 Peptide, zgc:112216 Peptide, Ptf1a/p48 Peptide, XPtf1a Peptide, PTF1-p48 Peptide, bHLHa29 Peptide, PTF1p48 Peptide, pancreas specific transcription factor, 1a Peptide, PTF1A Peptide, ptf1a Peptide, Ptf1a Peptide
    Hintergrund
    Ptf1a is a transcriptional activator. It binds to the E-box consensus sequence 5'-CANNTG-3' and may play a role in early and late pancreas development and differentiation. Ptf1a plays an important role in determining whether cells allocated to the pancreatic buds continue towards pancreatic organogenesis or revert back to duodenal fates and may be involved in the maintenance of exocrine pancreas-specific gene expression including ELA1 and amylase. It is required for the formation of pancreatic acinar and ductal cells. and plays an important role in cerebellar development.

    Alias Symbols: PTF1-p48, PTF1p48, bHLHa29

    Protein Size: 324
    Molekulargewicht
    35 kDa
    Gen-ID
    19213
    NCBI Accession
    NM_018809, NP_061279
    UniProt
    Q9QX98
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