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V-Akt Murine Thymoma Viral Oncogene Homolog 1 (AKT1) Peptid

AKT1 Wirt: Synthetic WB Without preservative
Rockland
Produktnummer ABIN1043545
Hersteller Produkt- Nr.: 000-000-260

Kurzübersicht für V-Akt Murine Thymoma Viral Oncogene Homolog 1 (AKT1) Peptid (ABIN1043545)

Target

AKT1 (V-Akt Murine Thymoma Viral Oncogene Homolog 1 (AKT1))

Quelle

  • 26
Synthetic

Applikation

Western Blotting (WB)
  • Protein-Typ

    Synthetic

    Hersteller Produkt- Nr.

    000-000-260

    Hersteller

    Rockland

    Verwendungszweck

    Substrate Peptide AKT/PKBa

    Produktmerkmale

    AKT1, serine/threonine kinase, apoptosis inhibitor substrate peptides, blocking peptide, control peptide

    Aufreinigung

    Greater than 98% specific peptide by HPLC analysis

    Reinheit

    Greater than 98% specific peptide by HPLC analysis
  • Applikationshinweise

    Application Note: AKT/PKBa Substrate control peptide should be used at 1.0 μg per 1.0 μL of antiserum in per assay.

    Western Blot Dilution: 1:500 - 1:2,000

    Other: User Optimized

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Reconstitution Buffer: Restore with deionized water (or equivalent)

    Reconstitution Volume: 500 μL

    Konzentration

    1.0 mg/mL

    Buffer

    Buffer: None

    Stabilizer: None

    Preservative: None

    Konservierungsmittel

    Without preservative

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Store vial at 2 - 8 ° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. Dilute only prior to immediate use.

    Haltbarkeit

    6 months
  • Target

    AKT1 (V-Akt Murine Thymoma Viral Oncogene Homolog 1 (AKT1))

    Hintergrund

    Synonyms: AKT1, serine/threonine kinase, apoptosis inhibitor substrate peptides, blocking peptide, control peptide

    Background: Akt is a serine/threonine kinase that enhances cell proliferation and inhibits apoptosis when activated. Akt associates with PI(3,4,5)P3) at the cell membrane through its pleckstrin homology domain and is activated through phosphorylation. 3-Phosphoinositide-dependent kinase-1 (PDK1) has been shown to first phosphorylate Akt at Thr308, then a second kinase phosphorylates Akt at position Ser473. In turn, Akt phosphorylates a host of proteins including the proapoptotic proteins BAD and pro-caspase-9, GSK3, p21WAF1, MDM2, and the forkhead (FKHR) family of transcription factors.

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