PERK Proteine
(Eukaryotic Translation Initiation Factor 2-alpha Kinase 3 (EIF2AK3))
The protein encoded by this gene phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2 (EIF2), leading to its inactivation, and thus to a rapid reduction of translational initiation and repression of global protein synthesis. It is a type I membrane protein located in the endoplasmic reticulum (ER), where it is induced by ER stress caused by malfolded proteins. Mutations in this gene are associated with Wolcott-Rallison syndrome. [provided by RefSeq, Jan 2010].
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EIF2AK3
Spezies: Human
Wirt: Insektenzellen
Recombinant
70 % - 90 %
Func
Active
EIF2AK3
Spezies: Human
Wirt: Escherichia coli (E. coli)
Recombinant
WB, SDS, ELISA
EIF2AK3
Spezies: Maus
Wirt: Escherichia coli (E. coli)
Recombinant
>90 %
WB, PC, SDS, Imm
EIF2AK3
Spezies: Human
Wirt: Escherichia coli (E. coli)
Recombinant
> 95 %
WB, PC, SDS, Imm
EIF2AK3
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
> 80 % as determined by SDS-PAGE and Coomassie blue staining
AbP, STD
1 image
EIF2AK3
Spezies: Human, Maus, Ratte
Wirt: Escherichia coli (E. coli)
Recombinant
WB, PC
Aliase für PERK Proteine
eukaryotic translation initiation factor 2 alpha kinase 3 (EIF2AK3) Proteineeukaryotic translation initiation factor 2 alpha kinase 3 (Eif2ak3) Proteine
AI427929 Proteine
EIF2AK3 Proteine
Pek Proteine
PEK Proteine
Perk Proteine
PERK Proteine
WRS Proteine
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